ETF PRO AIOctober 27, 2026
XBI SPDR S&P Biotech ETF
Fund tearsheet · data as of the latest session · October 27, 2026
ONE YEAR OF DAILY CLOSES
0.35%expense ratio
$10.4Bfund assets
+23.4%return, YTD
—return, 1 year
+$534Mnet flow, 1 month
+$1.3Bnet flow, 1 year
28.9%realized volatility, 1y
-14.9%worst drawdown, 1y
Top ten holdings
| 1 | MRNA MODERNA | 1.41% |
| 2 | TWST TWIST BIOSCIENCE | 1.40% |
| 3 | IOVA IOVANCE BIOTHERAPEUTICS | 0.56% |
| 4 | GRAL GRAIL INC | 0.90% |
| 5 | NTRA NATERA | 1.16% |
| 6 | HALO HALOZYME THERAPEUTICS | 1.03% |
| 7 | KYMR KYMERA THERAPEUTICS | 1.35% |
| 8 | ORKA Oruka Therapeutics | 1.37% |
| 9 | KOD KODIAK SCIENCES | 0.54% |
| 10 | REGN REGENERON PHARMACEUTICALS | 0.96% |
PREPARED WITH ETF PRO AI · PRIMARY MARKET DATA · INFORMATIONAL ONLY — NOT AN OFFER, RECOMMENDATION, OR INVESTMENT ADVICE · PAST PERFORMANCE DOES NOT GUARANTEE FUTURE RESULTS