XBISPDRINDEX
SPDR S&P Biotech ETF
$150.47+0.62% vs prior close
10817052-WK
Price through Oct 26, 2026 · Flows through Oct 23, 2026. Figures use the latest available records, not a live quote. Fund details retrieved Oct 26, 2026. Holdings snapshot retrieved Oct 26, 2026.
In seeking to track the performance of the S&P Biotechnology Select Industry Index (the "index"), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the biotechnology segment of the S&P Total Market Index ("S&P TMI").
XBI price
Source: Market tape, daily closes; price return, distributions not reinvested
Table
| Date | XBI close |
|---|---|
| Oct 27, 2025 | $111.59 |
| Oct 28, 2025 | $112.00 |
| Oct 29, 2025 | $110.96 |
| Oct 30, 2025 | $111.91 |
| Oct 31, 2025 | $112.71 |
| Nov 3, 2025 | $109.86 |
| Nov 4, 2025 | $108.04 |
| Nov 5, 2025 | $109.21 |
| Nov 6, 2025 | $109.29 |
| Nov 7, 2025 | $108.96 |
| Nov 10, 2025 | $110.09 |
| Nov 11, 2025 | $114.01 |
| Nov 12, 2025 | $114.11 |
| Nov 13, 2025 | $111.91 |
| Nov 14, 2025 | $114.01 |
| Nov 17, 2025 | $114.83 |
| Nov 18, 2025 | $115.18 |
| Nov 19, 2025 | $114.50 |
| Nov 20, 2025 | $113.83 |
| Nov 21, 2025 | $116.65 |
| Nov 24, 2025 | $119.58 |
| Nov 25, 2025 | $121.37 |
| Nov 26, 2025 | $122.85 |
| Nov 28, 2025 | $123.16 |
| Dec 1, 2025 | $119.85 |
| Dec 2, 2025 | $118.46 |
| Dec 3, 2025 | $121.83 |
| Dec 4, 2025 | $123.25 |
| Dec 5, 2025 | $123.41 |
| Dec 8, 2025 | $123.66 |
| Dec 9, 2025 | $121.19 |
| Dec 10, 2025 | $122.05 |
| Dec 11, 2025 | $123.02 |
| Dec 12, 2025 | $123.13 |
| Dec 15, 2025 | $122.84 |
| Dec 16, 2025 | $122.01 |
| Dec 17, 2025 | $120.94 |
| Dec 18, 2025 | $120.01 |
| Dec 19, 2025 | $123.43 |
| Dec 22, 2025 | $125.91 |
| Dec 23, 2025 | $124.89 |
| Dec 24, 2025 | $126.30 |
| Dec 26, 2025 | $124.98 |
| Dec 29, 2025 | $123.39 |
| Dec 30, 2025 | $121.67 |
| Dec 31, 2025 | $121.93 |
| Jan 2, 2026 | $121.52 |
| Jan 5, 2026 | $120.15 |
| Jan 6, 2026 | $122.09 |
| Jan 7, 2026 | $126.43 |
| Jan 8, 2026 | $123.71 |
| Jan 9, 2026 | $124.50 |
| Jan 12, 2026 | $123.93 |
| Jan 13, 2026 | $123.85 |
| Jan 14, 2026 | $126.82 |
| Jan 15, 2026 | $124.35 |
| Jan 16, 2026 | $124.18 |
| Jan 20, 2026 | $125.29 |
| Jan 21, 2026 | $128.18 |
| Jan 22, 2026 | $131.57 |
| Jan 23, 2026 | $128.04 |
| Jan 26, 2026 | $127.86 |
| Jan 27, 2026 | $128.53 |
| Jan 28, 2026 | $125.94 |
| Jan 29, 2026 | $126.74 |
| Jan 30, 2026 | $124.75 |
| Feb 2, 2026 | $127.35 |
| Feb 3, 2026 | $127.65 |
| Feb 4, 2026 | $125.29 |
| Feb 5, 2026 | $120.72 |
| Feb 6, 2026 | $125.51 |
| Feb 9, 2026 | $126.11 |
| Feb 10, 2026 | $125.34 |
| Feb 11, 2026 | $124.65 |
| Feb 12, 2026 | $123.18 |
| Feb 13, 2026 | $122.86 |
| Feb 17, 2026 | $124.63 |
| Feb 18, 2026 | $125.60 |
| Feb 19, 2026 | $126.74 |
| Feb 20, 2026 | $124.78 |
| Feb 23, 2026 | $126.97 |
| Feb 24, 2026 | $129.16 |
| Feb 25, 2026 | $128.28 |
| Feb 26, 2026 | $127.67 |
| Feb 27, 2026 | $127.37 |
| Mar 2, 2026 | $126.55 |
| Mar 3, 2026 | $123.50 |
| Mar 4, 2026 | $126.42 |
| Mar 5, 2026 | $123.90 |
| Mar 6, 2026 | $124.00 |
| Mar 9, 2026 | $127.12 |
| Mar 10, 2026 | $127.43 |
| Mar 11, 2026 | $126.38 |
| Mar 12, 2026 | $122.62 |
| Mar 13, 2026 | $121.83 |
| Mar 16, 2026 | $123.91 |
| Mar 17, 2026 | $124.19 |
| Mar 18, 2026 | $121.11 |
| Mar 19, 2026 | $122.33 |
| Mar 20, 2026 | $120.31 |
| Mar 23, 2026 | $121.70 |
| Mar 24, 2026 | $119.54 |
| Mar 25, 2026 | $123.92 |
| Mar 26, 2026 | $123.90 |
| Mar 27, 2026 | $119.59 |
| Mar 30, 2026 | $118.78 |
| Mar 31, 2026 | $127.73 |
| Apr 1, 2026 | $128.55 |
| Apr 2, 2026 | $128.96 |
| Apr 6, 2026 | $128.80 |
| Apr 7, 2026 | $128.85 |
| Apr 8, 2026 | $130.65 |
| Apr 9, 2026 | $131.82 |
| Apr 10, 2026 | $129.44 |
| Apr 13, 2026 | $132.05 |
| Apr 14, 2026 | $135.72 |
| Apr 15, 2026 | $136.45 |
| Apr 16, 2026 | $135.46 |
| Apr 17, 2026 | $138.67 |
| Apr 20, 2026 | $137.79 |
| Apr 21, 2026 | $136.39 |
| Apr 22, 2026 | $137.31 |
| Apr 23, 2026 | $134.49 |
| Apr 24, 2026 | $133.28 |
| Apr 27, 2026 | $133.04 |
| Apr 28, 2026 | $131.16 |
| Apr 29, 2026 | $128.90 |
| Apr 30, 2026 | $131.33 |
| May 1, 2026 | $130.42 |
| May 4, 2026 | $133.50 |
| May 5, 2026 | $133.79 |
| May 6, 2026 | $137.68 |
| May 7, 2026 | $133.66 |
| May 8, 2026 | $134.71 |
| May 11, 2026 | $134.75 |
| May 12, 2026 | $134.91 |
| May 13, 2026 | $135.85 |
| May 14, 2026 | $134.85 |
| May 15, 2026 | $130.69 |
| May 18, 2026 | $127.67 |
| May 19, 2026 | $126.79 |
| May 20, 2026 | $131.71 |
| May 21, 2026 | $132.78 |
| May 22, 2026 | $131.66 |
| May 26, 2026 | $133.35 |
| May 27, 2026 | $134.45 |
| May 28, 2026 | $135.99 |
| May 29, 2026 | $136.69 |
| Jun 1, 2026 | $133.62 |
| Jun 2, 2026 | $127.76 |
| Jun 3, 2026 | $129.83 |
| Jun 4, 2026 | $133.42 |
| Jun 5, 2026 | $128.67 |
| Jun 8, 2026 | $128.43 |
| Jun 9, 2026 | $131.38 |
| Jun 10, 2026 | $128.85 |
| Jun 11, 2026 | $132.74 |
| Jun 12, 2026 | $133.79 |
| Jun 15, 2026 | $136.40 |
| Jun 16, 2026 | $135.34 |
| Jun 17, 2026 | $139.39 |
| Jun 18, 2026 | $140.72 |
| Jun 22, 2026 | $145.86 |
| Jun 23, 2026 | $147.03 |
| Jun 24, 2026 | $149.71 |
| Jun 25, 2026 | $151.59 |
| Jun 26, 2026 | $155.38 |
| Jun 29, 2026 | $158.31 |
| Jun 30, 2026 | $158.25 |
| Jul 1, 2026 | $156.55 |
| Jul 2, 2026 | $160.46 |
| Jul 6, 2026 | $160.81 |
| Jul 7, 2026 | $163.87 |
| Jul 8, 2026 | $162.97 |
| Jul 9, 2026 | $164.28 |
| Jul 10, 2026 | $159.03 |
| Jul 13, 2026 | $155.34 |
| Jul 14, 2026 | $155.45 |
| Jul 15, 2026 | $156.22 |
| Jul 16, 2026 | $152.00 |
| Jul 17, 2026 | $154.26 |
| Jul 20, 2026 | $150.94 |
| Jul 21, 2026 | $154.50 |
| Jul 22, 2026 | $152.11 |
| Jul 23, 2026 | $152.23 |
| Jul 24, 2026 | $150.48 |
| Jul 27, 2026 | $150.59 |
| Jul 28, 2026 | $149.78 |
| Jul 29, 2026 | $147.91 |
| Jul 30, 2026 | $151.46 |
| Jul 31, 2026 | $147.01 |
| Aug 3, 2026 | $147.31 |
| Aug 4, 2026 | $151.88 |
| Aug 5, 2026 | $153.01 |
| Aug 6, 2026 | $154.50 |
| Aug 7, 2026 | $157.37 |
| Aug 10, 2026 | $158.03 |
| Aug 11, 2026 | $158.07 |
| Aug 12, 2026 | $159.39 |
| Aug 13, 2026 | $156.86 |
| Aug 14, 2026 | $157.41 |
| Aug 17, 2026 | $159.53 |
| Aug 18, 2026 | $160.11 |
| Aug 19, 2026 | $169.55 |
| Aug 20, 2026 | $163.38 |
| Aug 21, 2026 | $165.73 |
| Aug 24, 2026 | $164.17 |
| Aug 25, 2026 | $169.10 |
| Aug 26, 2026 | $168.39 |
| Aug 27, 2026 | $168.23 |
| Aug 28, 2026 | $162.38 |
| Aug 31, 2026 | $162.50 |
| Sep 1, 2026 | $163.40 |
| Sep 2, 2026 | $165.37 |
| Sep 3, 2026 | $164.38 |
| Sep 4, 2026 | $163.81 |
| Sep 8, 2026 | $161.93 |
| Sep 9, 2026 | $159.38 |
| Sep 10, 2026 | $156.82 |
| Sep 11, 2026 | $156.20 |
| Sep 14, 2026 | $157.60 |
| Sep 15, 2026 | $154.03 |
| Sep 16, 2026 | $154.18 |
| Sep 17, 2026 | $158.25 |
| Sep 18, 2026 | $156.72 |
| Sep 21, 2026 | $158.23 |
| Sep 22, 2026 | $161.87 |
| Sep 23, 2026 | $155.20 |
| Sep 24, 2026 | $156.05 |
| Sep 25, 2026 | $155.03 |
| Sep 28, 2026 | $156.61 |
| Sep 29, 2026 | $156.81 |
| Sep 30, 2026 | $157.68 |
| Oct 1, 2026 | $154.51 |
| Oct 2, 2026 | $154.43 |
| Oct 5, 2026 | $156.19 |
| Oct 6, 2026 | $150.90 |
| Oct 7, 2026 | $150.23 |
| Oct 8, 2026 | $149.29 |
| Oct 9, 2026 | $153.77 |
| Oct 12, 2026 | $151.40 |
| Oct 13, 2026 | $146.80 |
| Oct 14, 2026 | $146.77 |
| Oct 15, 2026 | $149.78 |
| Oct 16, 2026 | $144.32 |
| Oct 19, 2026 | $147.86 |
| Oct 20, 2026 | $153.24 |
| Oct 21, 2026 | $152.78 |
| Oct 22, 2026 | $151.64 |
| Oct 23, 2026 | $149.54 |
| Oct 26, 2026 | $150.47 |
Price history on file begins Oct 27, 2025, so 1Y shows all of it.
Weekly net flows, 1Y
Net inflow over the range: +$1.2B
- Inflow / above zero
- Outflow / below zero
Source: Daily creation and redemption records
Show as table
| Label | Value ($) |
|---|---|
| Oct 20 | −$70.5M |
| Oct 27 | $54M |
| Nov 3 | −$390.4M |
| Nov 10 | $838M |
| Nov 17 | −$20.1M |
| Nov 24 | $358.5M |
| Dec 1 | −$467.8M |
| Dec 8 | $13.9M |
| Dec 15 | $436M |
| Dec 22 | $69.8M |
| Dec 29 | −$424M |
| Jan 5 | $719M |
| Jan 12 | −$482.4M |
| Jan 19 | $299.6M |
| Jan 26 | −$262.9M |
| Feb 2 | −$571.4M |
| Feb 9 | $780.7M |
| Feb 16 | −$668.2M |
| Feb 23 | $15.2M |
| Mar 2 | $157.7M |
| Mar 9 | −$574.4M |
| Mar 16 | $219M |
| Mar 23 | −$132.3M |
| Mar 30 | $716.2M |
| Apr 6 | −$159.1M |
| Apr 13 | −$150.2M |
| Apr 20 | $53M |
| Apr 27 | −$71.1M |
| May 4 | −$224.4M |
| May 11 | $80.9M |
| May 18 | $188.5M |
| May 25 | −$296.4M |
| Jun 1 | −$37.5M |
| Jun 8 | $119.5M |
| Jun 15 | $321.1M |
| Jun 22 | $490.5M |
| Jun 29 | $69.2M |
| Jul 6 | −$7.7M |
| Jul 13 | $20.7M |
| Jul 20 | −$248.2M |
| Jul 27 | −$170.9M |
| Aug 3 | $210.4M |
| Aug 10 | $151M |
| Aug 17 | $290M |
| Aug 24 | $236.7M |
| Aug 31 | −$187.4M |
| Sep 7 | −$529.9M |
| Sep 14 | −$64.8M |
| Sep 21 | −$7.8M |
| Sep 28 | −$68.9M |
| Oct 5 | $257.9M |
| Oct 12 | $242.3M |
| Oct 19 | $103.2M |
The desk’s read
Money keeps arriving — +$534M of net inflows over the past month, about 5.2% of the fund's asset base, while the price has returned +23.4% so far this year. At 0.35% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.
COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH
$10.4Bassets under management
0.35%expense ratio · $35 per $10,000 a year
+$534Mnet flow, trailing month
9.7Mavg daily volume, 30 days
135holdings · US-domiciled
2006listed January 31, 2006 · beta 1.08
The book at a glance
CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS
Holdings
| # | Holding | Weight | Price | Day | 52-wk | |
|---|---|---|---|---|---|---|
| 1 | MRNAMODERNA | 1.41% | $198.85 | -0.6% | ||
| 2 | TWSTTWIST BIOSCIENCE | 1.40% | $145.25 | +3.8% | ||
| 3 | IOVAIOVANCE BIOTHERAPEUTICS | 0.56% | $13.78 | -2.2% | ||
| 4 | GRALGRAIL INC | 0.90% | $139.91 | +5.6% | ||
| 5 | NTRANATERA | 1.16% | $404.90 | +0.2% | ||
| 6 | HALOHALOZYME THERAPEUTICS | 1.03% | $128.01 | +1.9% | ||
| 7 | KYMRKYMERA THERAPEUTICS | 1.35% | $114.84 | +3.7% | ||
| 8 | ORKAOruka Therapeutics | 1.37% | $90.33 | +12.7% | ||
| 9 | KODKODIAK SCIENCES | 0.54% | $89.60 | +2.2% | ||
| 10 | REGNREGENERON PHARMACEUTICALS | 0.96% | $807.67 | +0.3% | ||
| 11 | PTGXPROTAGONIST THERAPEUTICS | 1.07% | $140.32 | +1.4% | ||
| 12 | PCVXVAXCYTE | 1.18% | $59.97 | -0.8% | ||
| 13 | AMGNAMGEN | 0.99% | $444.63 | +1.2% | ||
| 14 | GILDGILEAD SCIENCES | 0.96% | $158.69 | +1.7% | ||
| 15 | BIIBBIOGEN | 1.03% | $252.26 | +0.6% |
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- Healthcare100%
- Health Technology99.1%
- Health Services0.86%
- Other0.07%
Source: Portfolio composition, latest disclosure
Show as table
| Item | Value (%) |
|---|---|
| Healthcare | 100% |
| Health Technology | 99.1% |
| Health Services | 0.86% |
| Other | 0.07% |
Country weights
- United States97.18%
- United Kingdom1.29%
- Switzerland1.25%
- Bermuda0.34%
- Ireland0.27%
- Netherlands0.23%
Source: Portfolio composition, latest disclosure
Show as table
| Item | Value (%) |
|---|---|
| United States | 97.18% |
| United Kingdom | 1.29% |
| Switzerland | 1.25% |
| Bermuda | 0.34% |
| Ireland | 0.27% |
| Netherlands | 0.23% |
Performance
| 1 week | -1.8% |
| 1 month | -2.9% |
| 3 months | -0.0% |
| 6 months | +12.9% |
| YTD | +23.4% |
| 1 year | — |
| 3 years | — |
PRICE RETURN, DISTRIBUTIONS NOT REINVESTED
Net flows
| 1 week | +$368M |
| 1 month | +$534M |
| 3 months | +$462M |
| YTD | +$842M |
| 1 year | +$1.3B |
CREATION/REDEMPTION DOLLARS, DAILY RECORDS
Monthly net flows
- Inflow / above zero
- Outflow / below zero
Source: Daily creation/redemption records, trailing twelve months
Show as table
| Label | Value ($) |
|---|---|
| Nov | $785.9M |
| Dec | −$387.2M |
| Jan | $288.5M |
| Feb | −$443.7M |
| Mar | −$592.4M |
| Apr | $628.5M |
| May | −$228.6M |
| Jun | $922.5M |
| Jul | −$365.8M |
| Aug | $766.6M |
| Sep | −$690.4M |
| Oct | $556.5M |
The risk read
32%realized volatility, 30 days (annualized)
29%realized volatility, 1 year
-14.9%deepest fall from a peak, 1 year
-11.3%latest close versus that peak
The top holding is 1.5% of the book; the top ten carry 13%. Spread across 151+ names, it behaves like roughly 110 equally-weighted positions.
VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK
Options tape
3Kcalls · latest snapshot
12Kputs · latest snapshot
3.73put/call ratio
4.7Mshares traded
| Most-traded holdings, options premium | Bullish | Bearish |
|---|---|---|
| MRNA MODERNA | $52M | $70M |
| AMGN AMGEN | $2M | $4M |
| ABBV ABBVIE | $3M | $2M |
| JANX JANUX THERAPEUTICS | $2M | $2M |
| IOVA IOVANCE BIOTHERAPEUTICS | $1M | $2M |
TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES
The case against XBI
Due diligence cuts both ways. These funds sit on the same shelf and beat XBI on at least one dimension that matters — the fee, the asset base, or where the money is going.
| Fund | Fee | Assets | Flow, 1M | The case | |
|---|---|---|---|---|---|
| SPDW SPDR Portfolio Developed World ex-US ETF | 0.03% | $40.7B | +$609M | -32bp on fee · 4× the assets · +$609M in over the month | Head-to-head |
| SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF | 0.03% | $18.4B | +$199M | -32bp on fee · 2× the assets · +$199M in over the month | Head-to-head |
| IDEV iShares Core MSCI International Developed Markets ETF | 0.04% | $32.4B | +$497M | -31bp on fee · 3× the assets · +$497M in over the month | Head-to-head |
| IGSB iShares 1-5 Year Investment Grade Corporate Bond ETF | 0.04% | $23.7B | +$51M | -31bp on fee · 2× the assets · +$51M in over the month | Head-to-head |
| IGIB iShares 5-10 Year Investment Grade Corporate Bond ETF | 0.04% | $18.6B | +$412M | -31bp on fee · 2× the assets · +$412M in over the month | Head-to-head |