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Tuesday, October 27, 2026 · Today’s edition, 6:30 a.m. ETTue, Oct 27 · 6:30 a.m. editionSign inMy Desk 0EditionsSign in
GNOMGlobal XINDEX

Global X Genomics & Biotechnology ETF

$66.46+1.35% vs prior close
417252-WK

Price through Oct 26, 2026 · Flows through Aug 23, 2024. Figures use the latest available records, not a live quote. Fund details retrieved Oct 26, 2026. Holdings snapshot retrieved Oct 26, 2026.

The fund invests at least 80% of its total assets in the securities of the underlying index. The underlying index is designed to provide exposure to exchange-listed companies that are positioned to benefit from further advances in the field of genomic science and biotechnology, as well as applications thereof (collectively, "Genomics & Biotechnology Companies"), as defined by Solactive AG, the provider of the underlying index. The fund is non-diversified.

GNOM price

Source: Market tape, daily closes; price return, distributions not reinvested
Table
DateGNOM close
Oct 27, 2025$44.54
Oct 28, 2025$44.34
Oct 29, 2025$43.77
Oct 30, 2025$44.46
Oct 31, 2025$45.44
Nov 3, 2025$43.88
Nov 4, 2025$42.67
Nov 5, 2025$43.15
Nov 6, 2025$42.84
Nov 7, 2025$42.59
Nov 10, 2025$43.07
Nov 11, 2025$44.10
Nov 12, 2025$44.07
Nov 13, 2025$43.15
Nov 14, 2025$43.20
Nov 17, 2025$43.17
Nov 18, 2025$43.05
Nov 19, 2025$42.54
Nov 20, 2025$42.20
Nov 21, 2025$43.63
Nov 24, 2025$44.93
Nov 25, 2025$45.80
Nov 26, 2025$46.30
Nov 28, 2025$46.38
Dec 1, 2025$45.24
Dec 2, 2025$45.13
Dec 3, 2025$46.54
Dec 4, 2025$46.97
Dec 5, 2025$46.88
Dec 8, 2025$47.62
Dec 9, 2025$47.14
Dec 10, 2025$47.41
Dec 11, 2025$47.17
Dec 12, 2025$46.82
Dec 15, 2025$46.78
Dec 16, 2025$46.23
Dec 17, 2025$45.63
Dec 18, 2025$45.76
Dec 19, 2025$47.10
Dec 22, 2025$47.98
Dec 23, 2025$47.48
Dec 24, 2025$47.65
Dec 26, 2025$47.20
Dec 29, 2025$46.67
Dec 30, 2025$45.61
Dec 31, 2025$45.46
Jan 2, 2026$45.67
Jan 5, 2026$45.90
Jan 6, 2026$47.83
Jan 7, 2026$48.68
Jan 8, 2026$47.50
Jan 9, 2026$47.36
Jan 12, 2026$47.37
Jan 13, 2026$47.80
Jan 14, 2026$48.37
Jan 15, 2026$47.85
Jan 16, 2026$47.81
Jan 20, 2026$48.40
Jan 21, 2026$49.76
Jan 22, 2026$50.59
Jan 23, 2026$49.50
Jan 26, 2026$49.31
Jan 27, 2026$49.18
Jan 28, 2026$48.12
Jan 29, 2026$48.44
Jan 30, 2026$47.69
Feb 2, 2026$47.93
Feb 3, 2026$47.51
Feb 4, 2026$46.79
Feb 5, 2026$45.10
Feb 6, 2026$46.13
Feb 9, 2026$46.20
Feb 10, 2026$46.34
Feb 11, 2026$46.16
Feb 12, 2026$45.41
Feb 13, 2026$45.81
Feb 17, 2026$46.32
Feb 18, 2026$46.95
Feb 19, 2026$47.25
Feb 20, 2026$46.88
Feb 23, 2026$46.83
Feb 24, 2026$47.51
Feb 25, 2026$47.44
Feb 26, 2026$47.81
Feb 27, 2026$47.66
Mar 2, 2026$47.12
Mar 3, 2026$45.91
Mar 4, 2026$47.07
Mar 5, 2026$45.77
Mar 6, 2026$45.20
Mar 9, 2026$46.21
Mar 10, 2026$45.33
Mar 11, 2026$45.00
Mar 12, 2026$43.61
Mar 13, 2026$43.24
Mar 16, 2026$43.67
Mar 17, 2026$43.97
Mar 18, 2026$42.98
Mar 19, 2026$43.37
Mar 20, 2026$42.50
Mar 23, 2026$42.78
Mar 24, 2026$42.53
Mar 25, 2026$43.97
Mar 26, 2026$43.32
Mar 27, 2026$41.50
Mar 30, 2026$41.40
Mar 31, 2026$43.74
Apr 1, 2026$44.19
Apr 2, 2026$44.19
Apr 6, 2026$44.05
Apr 7, 2026$44.01
Apr 8, 2026$45.03
Apr 9, 2026$44.63
Apr 10, 2026$43.90
Apr 13, 2026$44.80
Apr 14, 2026$46.44
Apr 15, 2026$46.90
Apr 16, 2026$46.21
Apr 17, 2026$47.29
Apr 20, 2026$47.62
Apr 21, 2026$47.26
Apr 22, 2026$47.51
Apr 23, 2026$46.16
Apr 24, 2026$45.97
Apr 27, 2026$45.55
Apr 28, 2026$44.87
Apr 29, 2026$43.95
Apr 30, 2026$45.34
May 1, 2026$45.42
May 4, 2026$46.31
May 5, 2026$45.55
May 6, 2026$46.98
May 7, 2026$46.36
May 8, 2026$46.39
May 11, 2026$46.26
May 12, 2026$46.79
May 13, 2026$46.15
May 14, 2026$45.59
May 15, 2026$44.31
May 18, 2026$44.01
May 19, 2026$43.90
May 20, 2026$45.52
May 21, 2026$46.36
May 22, 2026$46.54
May 26, 2026$47.02
May 27, 2026$47.96
May 28, 2026$49.51
May 29, 2026$49.68
Jun 1, 2026$48.53
Jun 2, 2026$48.05
Jun 3, 2026$49.01
Jun 4, 2026$50.71
Jun 5, 2026$48.56
Jun 8, 2026$47.78
Jun 9, 2026$48.90
Jun 10, 2026$47.92
Jun 11, 2026$49.13
Jun 12, 2026$48.95
Jun 15, 2026$50.10
Jun 16, 2026$50.01
Jun 17, 2026$51.30
Jun 18, 2026$52.07
Jun 22, 2026$51.76
Jun 23, 2026$52.23
Jun 24, 2026$53.78
Jun 25, 2026$54.96
Jun 26, 2026$56.27
Jun 29, 2026$57.12
Jun 30, 2026$56.83
Jul 1, 2026$57.78
Jul 2, 2026$58.40
Jul 6, 2026$58.83
Jul 7, 2026$58.32
Jul 8, 2026$57.34
Jul 9, 2026$58.54
Jul 10, 2026$56.65
Jul 13, 2026$55.61
Jul 14, 2026$55.76
Jul 15, 2026$55.99
Jul 16, 2026$55.10
Jul 17, 2026$54.92
Jul 20, 2026$53.57
Jul 21, 2026$54.85
Jul 22, 2026$54.70
Jul 23, 2026$54.90
Jul 24, 2026$53.99
Jul 27, 2026$53.69
Jul 28, 2026$53.90
Jul 29, 2026$53.72
Jul 30, 2026$55.39
Jul 31, 2026$54.17
Aug 3, 2026$54.89
Aug 4, 2026$55.81
Aug 5, 2026$56.32
Aug 6, 2026$55.71
Aug 7, 2026$58.17
Aug 10, 2026$59.76
Aug 11, 2026$59.68
Aug 12, 2026$59.53
Aug 13, 2026$59.06
Aug 14, 2026$58.31
Aug 17, 2026$59.09
Aug 18, 2026$58.51
Aug 19, 2026$66.48
Aug 20, 2026$64.90
Aug 21, 2026$66.77
Aug 24, 2026$65.13
Aug 25, 2026$67.85
Aug 26, 2026$67.35
Aug 27, 2026$67.24
Aug 28, 2026$64.81
Aug 31, 2026$64.42
Sep 1, 2026$64.76
Sep 2, 2026$65.68
Sep 3, 2026$64.97
Sep 4, 2026$64.26
Sep 8, 2026$63.44
Sep 9, 2026$62.75
Sep 10, 2026$61.97
Sep 11, 2026$62.22
Sep 14, 2026$63.57
Sep 15, 2026$63.65
Sep 16, 2026$63.58
Sep 17, 2026$66.92
Sep 18, 2026$66.40
Sep 21, 2026$67.60
Sep 22, 2026$69.28
Sep 23, 2026$67.76
Sep 24, 2026$70.25
Sep 25, 2026$70.21
Sep 28, 2026$70.30
Sep 29, 2026$70.35
Sep 30, 2026$70.48
Oct 1, 2026$68.78
Oct 2, 2026$69.62
Oct 5, 2026$72.30
Oct 6, 2026$67.60
Oct 7, 2026$66.85
Oct 8, 2026$65.83
Oct 9, 2026$68.75
Oct 12, 2026$66.64
Oct 13, 2026$65.34
Oct 14, 2026$65.91
Oct 15, 2026$67.01
Oct 16, 2026$64.31
Oct 19, 2026$65.58
Oct 20, 2026$67.65
Oct 21, 2026$68.72
Oct 22, 2026$66.01
Oct 23, 2026$65.58
Oct 26, 2026$66.46

Price history on file begins Oct 27, 2025, so 1Y shows all of it.

Weekly net flows, 1Y

Net outflow over the range: −$369M

  • Inflow / above zero
  • Outflow / below zero
−$300.1MOct 30Nov 20Dec 11Jan 1Jan 22Feb 12Mar 4Mar 25Apr 15May 6May 27Jun 17Jul 8Jul 29−$15KAug 19−$300.1MOct 30Dec 4Jan 8Feb 12Mar 18Apr 22May 27Jul 1−$15KAug 19−$300.1MOct 30Jan 15Apr 1Jun 17−$15KAug 19
Source: Daily creation and redemption records
Show as table
LabelValue ($)
Oct 30−$300.1M
Nov 6−$5.7M
Nov 13−$12.7K
Nov 20$182.3K
Nov 27−$227.7K
Dec 4$151.4K
Dec 11$163.8K
Dec 18−$20.1M
Dec 25$135.4K
Jan 1−$11.7M
Jan 8$110.5K
Jan 15−$205.8K
Jan 22$56.1K
Jan 29$167.5K
Feb 5−$314.9K
Feb 12$51.2K
Feb 19$90.1K
Feb 26−$144.5K
Mar 4$10.5M
Mar 11$29.6M
Mar 18$6.8M
Mar 25−$4.7M
Apr 1−$126.2K
Apr 8$72.4K
Apr 15$102.6K
Apr 22−$203.3K
Apr 29$227.8K
May 6−$136.2K
May 13−$129.3K
May 20$67.5K
May 27$124.5K
Jun 3$117K
Jun 10−$42.9K
Jun 17−$244.3K
Jun 24−$11.9K
Jul 1$84.1K
Jul 8−$6.5M
Jul 15−$69.2M
Jul 22$1.8M
Jul 29$108.7K
Aug 5−$38.6K
Aug 12$13.6K
Aug 19−$15K
The desk’s read

Recent fund-flow records are unavailable, while the price has returned +46.2% so far this year. At 0.50% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$85Massets under management
0.50%expense ratio · $50 per $10,000 a year
—net flow, trailing month
39Kavg daily volume, 30 days
41holdings · US-domiciled
2019listed April 5, 2019 · beta 1.24
The book at a glance
MRNA-0.6%TWST+3.8%TXG+2.0%ILMN+0.6%NTRA+0.2%GH+2.5%QGEN-0.0%TECH+0.2%VRTX-1.2%BMRN-0.4%CAI+1.4%VCYT+0.6%CRSP-0.8%CDNA-0.2%BNTX-1.4%ARWR+1.7%PRAX+5.7%LEGN+5.8%LLY+0.4%GILD+1.7%BEAM-1.1%BLLN+3.4%SRPT+1.4%AZN+0.3%WGS+9.1%RARE+2.7%DHR+1.1%VIR+4.4%NTLA+0.4%STOKPSNLMRVI

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS

Holdings
#HoldingWeightPriceDay52-wk
1MRNAMODERNA11.05%$198.85-0.6%
2TWSTTWIST BIOSCIENCE6.70%$145.25+3.8%
3TXG10X GENOMICS6.38%$72.96+2.0%
4ILMNILLUMINA6.09%$271.04+0.6%
5NTRANATERA5.50%$404.90+0.2%
6GHGUARDANT HEALTH5.22%$173.25+2.5%
7QGENQIAGEN NV3.26%$50.37-0.0%
8TECHBIO-TECHNE3.56%$72.69+0.2%
9VRTXVERTEX PHARMACEUTICALS3.33%$517.49-1.2%
10BMRNBIOMARIN PHARMACEUTICAL2.94%$55.75-0.4%
11CAICaris Life Sciences2.68%$32.45+1.4%
12VCYTVERACYTE2.57%$48.20+0.6%
13CRSPCRISPR THERAPEUTICS AG2.63%$49.01-0.8%
14CDNACAREDX2.17%$69.10-0.2%
15BNTXBIONTECH SE2.54%$86.86-1.4%

The full book, free with one sign-in.

Top 15 positions are open to everyone. Sign in once and every fund’s complete holdings — plus watchlists and flow alerts — unlock across the network.

Sign in to see all 41

Sector weights

  • Healthcare100%
  • Health Technology99.08%
  • Health Services0.75%
  • Miscellaneous0.15%
  • Other0.06%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
Healthcare100%
Health Technology99.08%
Health Services0.75%
Miscellaneous0.15%
Other0.06%

Country weights

  • United States92.49%
  • Hong Kong3.81%
  • Germany3.28%
  • China3.13%
  • Switzerland3.08%
  • Japan0.59%
  • Netherlands0.55%
  • Italy0.11%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
United States92.49%
Hong Kong3.81%
Germany3.28%
China3.13%
Switzerland3.08%
Japan0.59%
Netherlands0.55%
Italy0.11%
Performance
1 week-1.8%
1 month-5.3%
3 months+23.1%
6 months+44.6%
YTD+46.2%
1 year—
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week—
1 month—
3 months—
YTD—
1 year—

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows

  • Inflow / above zero
  • Outflow / below zero
−$296.6MOct−$9.1MNov−$19.7MDec−$11.8MJan−$862Feb+$42.1MMar−$195.2KApr+$195.1KMay−$182.1KJun−$73.9MJul+$171KAug−$296.6MOctNovDecJanFebMarAprMayJunJul+$171KAug−$296.6MOctDecFebAprJun+$171KAug
Source: Daily creation/redemption records, trailing twelve months
Show as table
LabelValue ($)
Oct−$296.6M
Nov−$9.1M
Dec−$19.7M
Jan−$11.8M
Feb−$862
Mar$42.1M
Apr−$195.2K
May$195.1K
Jun−$182.1K
Jul−$73.9M
Aug$171K
The risk read
46%realized volatility, 30 days (annualized)
33%realized volatility, 1 year
-18.2%deepest fall from a peak, 1 year
-8.1%latest close versus that peak

The top holding is 11.1% of the book; the top ten carry 56%. Spread across 50+ names, it behaves like roughly 23 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
—calls · latest snapshot
—puts · latest snapshot
—put/call ratio
16Kshares traded
Most-traded holdings, options premiumBullishBearish
MRNA MODERNA$52M$70M
LLY ELI LILLY$29M$32M
AZN ASTRAZENECA$1M$1M
DHR DANAHER$602,952$1M
WGS GENEDX HOLDINGS$733,495$1M

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against GNOM

Due diligence cuts both ways. These funds sit on the same shelf and beat GNOM on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW SPDR Portfolio Developed World ex-US ETF0.03%$40.7B+$609M-47bp on fee · 480× the assets · +$609M in over the monthHead-to-head
BBUS JPMorgan BetaBuilders U.S. Equity ETF0.02%$9.6B+$187M-48bp on fee · 113× the assets · +$187M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.4B+$199M-47bp on fee · 217× the assets · +$199M in over the monthHead-to-head
SPYG State Street SPDR Portfolio S&P 500 Growth ETF0.04%$57.9B+$717M-46bp on fee · 683× the assets · +$717M in over the monthHead-to-head
SPTM State Street SPDR Portfolio S&P 1500 Composite Stock Market ETF0.03%$14.2B+$235M-47bp on fee · 168× the assets · +$235M in over the monthHead-to-head
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