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Wednesday, October 28, 2026 · Today’s edition, 6:30 a.m. ETWed, Oct 28 · 6:30 a.m. editionSign inMy Desk 0EditionsSign in
GNOMGlobal XINDEX

Global X Genomics & Biotechnology ETF

$68.80+3.52% vs prior close
417252-WK

Price through Oct 27, 2026 · Flows through Aug 23, 2024. Figures use the latest available records, not a live quote. Fund details retrieved Oct 27, 2026. Holdings snapshot retrieved Oct 27, 2026.

The fund invests at least 80% of its total assets in the securities of the underlying index. The underlying index is designed to provide exposure to exchange-listed companies that are positioned to benefit from further advances in the field of genomic science and biotechnology, as well as applications thereof (collectively, "Genomics & Biotechnology Companies"), as defined by Solactive AG, the provider of the underlying index. The fund is non-diversified.

GNOM price

Source: Market tape, daily closes; price return, distributions not reinvested
Table
DateGNOM close
Jul 27, 2026$53.69
Jul 28, 2026$53.90
Jul 29, 2026$53.72
Jul 30, 2026$55.39
Jul 31, 2026$54.17
Aug 3, 2026$54.89
Aug 4, 2026$55.81
Aug 5, 2026$56.32
Aug 6, 2026$55.71
Aug 7, 2026$58.17
Aug 10, 2026$59.76
Aug 11, 2026$59.68
Aug 12, 2026$59.53
Aug 13, 2026$59.06
Aug 14, 2026$58.31
Aug 17, 2026$59.09
Aug 18, 2026$58.51
Aug 19, 2026$66.48
Aug 20, 2026$64.90
Aug 21, 2026$66.77
Aug 24, 2026$65.13
Aug 25, 2026$67.85
Aug 26, 2026$67.35
Aug 27, 2026$67.24
Aug 28, 2026$64.81
Aug 31, 2026$64.42
Sep 1, 2026$64.76
Sep 2, 2026$65.68
Sep 3, 2026$64.97
Sep 4, 2026$64.26
Sep 8, 2026$63.44
Sep 9, 2026$62.75
Sep 10, 2026$61.97
Sep 11, 2026$62.22
Sep 14, 2026$63.57
Sep 15, 2026$63.65
Sep 16, 2026$63.58
Sep 17, 2026$66.92
Sep 18, 2026$66.40
Sep 21, 2026$67.60
Sep 22, 2026$69.28
Sep 23, 2026$67.76
Sep 24, 2026$70.25
Sep 25, 2026$70.21
Sep 28, 2026$70.30
Sep 29, 2026$70.35
Sep 30, 2026$70.48
Oct 1, 2026$68.78
Oct 2, 2026$69.62
Oct 5, 2026$72.30
Oct 6, 2026$67.60
Oct 7, 2026$66.85
Oct 8, 2026$65.83
Oct 9, 2026$68.75
Oct 12, 2026$66.64
Oct 13, 2026$65.34
Oct 14, 2026$65.91
Oct 15, 2026$67.01
Oct 16, 2026$64.31
Oct 19, 2026$65.58
Oct 20, 2026$67.65
Oct 21, 2026$68.72
Oct 22, 2026$66.01
Oct 23, 2026$65.58
Oct 26, 2026$66.46
Oct 27, 2026$68.80

Weekly net flows, 3M

Net outflow over the range: −$74M

  • Inflow / above zero
  • Outflow / below zero
May 20May 27Jun 3Jun 10Jun 17Jun 24Jul 1Jul 8−$69.2MJul 15Jul 22Jul 29Aug 5Aug 12−$15KAug 19May 20Jun 3Jun 17Jul 1−$69.2MJul 15Jul 29−$15KAug 19May 20Jun 17−$69.2MJul 15−$15KAug 19
Source: Daily creation and redemption records
Show as table
LabelValue ($)
May 20$80.1K
May 27$124.5K
Jun 3$117K
Jun 10−$42.9K
Jun 17−$244.3K
Jun 24−$11.9K
Jul 1$84.1K
Jul 8−$6.5M
Jul 15−$69.2M
Jul 22$1.8M
Jul 29$108.7K
Aug 5−$38.6K
Aug 12$13.6K
Aug 19−$15K
The desk’s read

Recent fund-flow records are unavailable, while the price has returned +51.4% so far this year. At 0.50% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$85Massets under management
0.50%expense ratio · $50 per $10,000 a year
—net flow, trailing month
38Kavg daily volume, 30 days
41holdings · US-domiciled
2019listed April 5, 2019 · beta 1.25
The book at a glance
MRNA+4.6%TWST+10.1%TXG+6.9%ILMN+3.1%GH+2.8%NTRA+1.5%QGEN-0.4%TECH-0.1%VRTX+0.7%CAI+3.7%VCYT+4.3%BMRN-0.7%CRSP+5.0%CDNA+2.1%LEGN+5.7%BNTX+0.2%ARWR+0.1%PRAX+0.1%LLY+0.2%BEAM+4.7%GILD+0.2%BLLN+2.3%SRPT+5.1%AZN-1.2%WGS+2.4%RARE+4.2%DHR-0.4%NTLA+9.1%VIR+4.8%BMY-0.1%STOK+2.6%PSNL

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS

Holdings
#HoldingWeightPriceDay52-wk
1MRNAMODERNA11.05%$207.97+4.6%
2TWSTTWIST BIOSCIENCE6.70%$159.85+10.1%
3TXG10X GENOMICS6.38%$78.02+6.9%
4ILMNILLUMINA6.09%$279.47+3.1%
5GHGUARDANT HEALTH5.22%$178.06+2.8%
6NTRANATERA5.50%$410.82+1.5%
7QGENQIAGEN NV3.26%$50.17-0.4%
8TECHBIO-TECHNE3.56%$72.60-0.1%
9VRTXVERTEX PHARMACEUTICALS3.33%$521.03+0.7%
10CAICaris Life Sciences2.68%$33.67+3.7%
11VCYTVERACYTE2.57%$50.28+4.3%
12BMRNBIOMARIN PHARMACEUTICAL2.94%$55.35-0.7%
13CRSPCRISPR THERAPEUTICS AG2.63%$51.47+5.0%
14CDNACAREDX2.17%$70.53+2.1%
15LEGNLEGEND BIOTECH1.97%$21.56+5.7%

The full book, free with one sign-in.

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Sector weights

  • Healthcare100%
  • Health Technology99.08%
  • Health Services0.75%
  • Miscellaneous0.15%
  • Other0.06%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
Healthcare100%
Health Technology99.08%
Health Services0.75%
Miscellaneous0.15%
Other0.06%

Country weights

  • United States92.49%
  • Hong Kong3.81%
  • Germany3.28%
  • China3.13%
  • Switzerland3.08%
  • Japan0.59%
  • Netherlands0.55%
  • Italy0.11%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
United States92.49%
Hong Kong3.81%
Germany3.28%
China3.13%
Switzerland3.08%
Japan0.59%
Netherlands0.55%
Italy0.11%
Performance
1 week+0.1%
1 month-2.0%
3 months+28.1%
6 months+49.7%
YTD+51.4%
1 year+54.5%
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week—
1 month—
3 months—
YTD—
1 year—

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows

  • Inflow / above zero
  • Outflow / below zero
−$296.6MOct−$9.1MNov−$19.7MDec−$11.8MJan−$862Feb+$42.1MMar−$195.2KApr+$195.1KMay−$182.1KJun−$73.9MJul+$171KAug−$296.6MOctNovDecJanFebMarAprMayJunJul+$171KAug−$296.6MOctDecFebAprJun+$171KAug
Source: Daily creation/redemption records, trailing twelve months
Show as table
LabelValue ($)
Oct−$296.6M
Nov−$9.1M
Dec−$19.7M
Jan−$11.8M
Feb−$862
Mar$42.1M
Apr−$195.2K
May$195.1K
Jun−$182.1K
Jul−$73.9M
Aug$171K
The risk read
46%realized volatility, 30 days (annualized)
33%realized volatility, 1 year
-18.2%deepest fall from a peak, 1 year
-4.8%latest close versus that peak

The top holding is 11.1% of the book; the top ten carry 56%. Spread across 50+ names, it behaves like roughly 23 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
5calls · latest snapshot
—puts · latest snapshot
—put/call ratio
17Kshares traded
Most-traded holdings, options premiumBullishBearish
MRNA MODERNA$52M$53M
LLY ELI LILLY$24M$26M
NTRA NATERA$2M$2M
AZN ASTRAZENECA$1M$2M
GILD GILEAD SCIENCES$2M$738,877

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against GNOM

Due diligence cuts both ways. These funds sit on the same shelf and beat GNOM on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW SPDR Portfolio Developed World ex-US ETF0.03%$40.7B+$609M-47bp on fee · 481× the assets · +$609M in over the monthHead-to-head
BBUS JPMorgan BetaBuilders U.S. Equity ETF0.02%$9.6B+$187M-48bp on fee · 113× the assets · +$187M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.4B+$199M-47bp on fee · 217× the assets · +$199M in over the monthHead-to-head
SPYG State Street SPDR Portfolio S&P 500 Growth ETF0.04%$57.9B+$717M-46bp on fee · 683× the assets · +$717M in over the monthHead-to-head
SPTM State Street SPDR Portfolio S&P 1500 Composite Stock Market ETF0.03%$14.2B+$235M-47bp on fee · 168× the assets · +$235M in over the monthHead-to-head
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