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Tuesday, October 27, 2026 · Today’s edition, 6:30 a.m. ETTue, Oct 27 · 6:30 a.m. editionSign inMy Desk 0EditionsSign in
IDNAISharesINDEX

iShares Genomics Immunology and Healthcare ETF

$40.95+0.10% vs prior close
254352-WK

Price through Oct 26, 2026 · Flows through Oct 26, 2026. Figures use the latest available records, not a live quote. Fund details retrieved Oct 26, 2026. Holdings snapshot retrieved Oct 26, 2026.

The fund generally will invest at least 80% of its assets in the component securities of the index and in investments that have economic characteristics that are substantially identical to the component securities of the index and may invest up to 20% of its assets in certain futures, options and swap contracts, cash and cash equivalents. The index is composed of developed and emerging market companies that could benefit from the long-term growth and innovation in genomics, immunology and bioengineering. It is non-diversified.

IDNA price

Source: Market tape, daily closes; price return, distributions not reinvested
Table
DateIDNA close
Jul 27, 2026$32.24
Jul 28, 2026$32.45
Jul 29, 2026$32.15
Jul 30, 2026$32.79
Jul 31, 2026$32.33
Aug 3, 2026$32.42
Aug 4, 2026$32.91
Aug 5, 2026$33.34
Aug 6, 2026$33.58
Aug 7, 2026$34.78
Aug 10, 2026$35.26
Aug 11, 2026$35.20
Aug 12, 2026$35.42
Aug 13, 2026$35.24
Aug 14, 2026$35.23
Aug 17, 2026$35.86
Aug 18, 2026$35.98
Aug 19, 2026$40.75
Aug 20, 2026$39.29
Aug 21, 2026$40.08
Aug 24, 2026$39.67
Aug 25, 2026$41.48
Aug 26, 2026$40.63
Aug 27, 2026$40.60
Aug 28, 2026$39.29
Aug 31, 2026$39.26
Sep 1, 2026$39.67
Sep 2, 2026$40.20
Sep 3, 2026$40.29
Sep 4, 2026$39.77
Sep 8, 2026$39.23
Sep 9, 2026$38.60
Sep 10, 2026$37.88
Sep 11, 2026$38.06
Sep 14, 2026$38.74
Sep 15, 2026$38.59
Sep 16, 2026$38.70
Sep 17, 2026$40.00
Sep 18, 2026$39.83
Sep 21, 2026$40.63
Sep 22, 2026$41.74
Sep 23, 2026$40.78
Sep 24, 2026$41.69
Sep 25, 2026$41.77
Sep 28, 2026$41.79
Sep 29, 2026$42.63
Sep 30, 2026$42.32
Oct 1, 2026$41.64
Oct 2, 2026$41.65
Oct 5, 2026$42.72
Oct 6, 2026$40.87
Oct 7, 2026$40.88
Oct 8, 2026$40.42
Oct 9, 2026$42.17
Oct 12, 2026$41.56
Oct 13, 2026$40.79
Oct 14, 2026$41.28
Oct 15, 2026$42.05
Oct 16, 2026$40.54
Oct 19, 2026$40.96
Oct 20, 2026$42.58
Oct 21, 2026$42.70
Oct 22, 2026$41.04
Oct 23, 2026$40.91
Oct 26, 2026$40.95

Weekly net flows, 3M

Net inflow over the range: +$79M

  • Inflow / above zero
  • Outflow / below zero
Jul 27Aug 3Aug 10Aug 17Aug 24Aug 31Sep 7Sep 14Sep 21+$25.2MSep 28Oct 5Oct 12Oct 19$0Oct 26Jul 27Aug 10Aug 24Sep 7Sep 21+$25.2MOct 5$0Oct 26Jul 27Aug 24Sep 21+$25.2M$0Oct 26
Source: Daily creation and redemption records
Show as table
LabelValue ($)
Jul 27$2.7M
Aug 3−$2.7M
Aug 10$7M
Aug 17$6M
Aug 24$12.3M
Aug 31$2M
Sep 7$5.7M
Sep 14$1.9M
Sep 21$2M
Sep 28$25.2M
Oct 5$6.4M
Oct 12$0
Oct 19$10.3M
Oct 26$0
The desk’s read

Money keeps arriving — +$42M of net inflows over the past month, about 13.1% of the fund's asset base, while the price has returned +56.4% so far this year. At 0.47% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$321Massets under management
0.47%expense ratio · $47 per $10,000 a year
+$42Mnet flow, trailing month
198Kavg daily volume, 30 days
63holdings · US-domiciled
2019listed June 11, 2019 · beta 1.02
The book at a glance
MRNA-0.6%TWST+3.8%GSK+0.7%IOVA-2.2%REGN+0.3%CAI+1.4%EXEL+0.9%RVMD-1.7%MRK-3.2%VRTX-1.2%INCY-2.1%ROP+0.8%BNTX-1.4%IBRX-5.0%ABCL+2.2%IDYA-5.3%RCUS-4.2%VIR+4.4%NVAX-3.1%CRSP-0.8%NUVB-1.3%PSNL+0.2%JANX+0.2%RIGLKURAVSTMCRVSGMAB+2.0%SAN-3.7%45023.8%

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS

Holdings
#HoldingWeightPriceDay52-wk
1MRNAMODERNA12.14%$198.85-0.6%
2TWSTTWIST BIOSCIENCE5.82%$145.25+3.8%
3GSKGSK2.81%$51.10+0.7%
4IOVAIOVANCE BIOTHERAPEUTICS4.94%$13.78-2.2%
5REGNREGENERON PHARMACEUTICALS3.65%$807.67+0.3%
6CAICaris Life Sciences3.54%$32.45+1.4%
7EXELEXELIXIS3.52%$65.11+0.9%
8RVMDREVOLUTION MEDICINES3.61%$183.90-1.7%
9MRKMERCK & CO3.46%$140.61-3.2%
10VRTXVERTEX PHARMACEUTICALS3.37%$517.49-1.2%
11INCYINCYTE3.25%$113.31-2.1%
12ROPROPER TECHNOLOGIES3.31%$441.65+0.8%
13BNTXBIONTECH SE2.88%$86.86-1.4%
14IBRXIMMUNITYBIO2.79%$7.81-5.0%
15ABCLABCELLERA BIOLOGICS2.50%$12.08+2.2%

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Sector weights

  • Health Care99.75%
  • Cash and/or Derivatives0.24%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
Health Care99.75%
Cash and/or Derivatives0.24%

Country weights

  • United States66.72%
  • Germany6.27%
  • France5.7%
  • Japan5.49%
  • Denmark4.63%
  • Switzerland3.32%
  • United Kingdom2.83%
  • Canada2.5%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
United States66.72%
Germany6.27%
France5.7%
Japan5.49%
Denmark4.63%
Switzerland3.32%
United Kingdom2.83%
Canada2.5%
Performance
1 week-3.8%
1 month-2.0%
3 months+27.8%
6 months+36.6%
YTD+56.4%
1 year—
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week+$10M
1 month+$42M
3 months+$79M
YTD+$108M
1 year+$107M

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows

  • Inflow / above zero
  • Outflow / below zero
+$1.3MOct−$5.2MNov+$4MDec$0Jan+$3.1MFeb+$3MMar+$7.7MApr$0May+$18.3MJul+$22.6MAug+$20.1MSep+$33.6MOct+$1.3MOct−$5.2MNov+$4MDec$0Jan+$3.1MFeb+$3MMar+$7.7MApr$0May+$18.3MJul+$22.6MAug+$20.1MSep+$33.6MOctOctDecFebAprJul+$33.6MOct
Source: Daily creation/redemption records, trailing twelve months
Show as table
LabelValue ($)
Oct$1.3M
Nov−$5.2M
Dec$4M
Jan$0
Feb$3.1M
Mar$3M
Apr$7.7M
May$0
Jul$18.3M
Aug$22.6M
Sep$20.1M
Oct$33.6M
The risk read
38%realized volatility, 30 days (annualized)
29%realized volatility, 1 year
-10.7%deepest fall from a peak, 1 year
-4.1%latest close versus that peak

The top holding is 12.1% of the book; the top ten carry 49%. Spread across 53+ names, it behaves like roughly 24 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
1calls · latest snapshot
1puts · latest snapshot
1.00put/call ratio
60Kshares traded
Most-traded holdings, options premiumBullishBearish
MRNA MODERNA$52M$70M
MRK MERCK & CO$4M$5M
JANX JANUX THERAPEUTICS$2M$2M
IOVA IOVANCE BIOTHERAPEUTICS$1M$2M
VRTX VERTEX PHARMACEUTICALS$1M$454,914

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against IDNA

Due diligence cuts both ways. These funds sit on the same shelf and beat IDNA on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW SPDR Portfolio Developed World ex-US ETF0.03%$40.7B+$609M-44bp on fee · 127× the assets · +$609M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.4B+$199M-44bp on fee · 57× the assets · +$199M in over the monthHead-to-head
IDEV iShares Core MSCI International Developed Markets ETF0.04%$32.4B+$497M-43bp on fee · 101× the assets · +$497M in over the monthHead-to-head
IGSB iShares 1-5 Year Investment Grade Corporate Bond ETF0.04%$23.7B+$51M-43bp on fee · 74× the assets · +$51M in over the monthHead-to-head
IGIB iShares 5-10 Year Investment Grade Corporate Bond ETF0.04%$18.6B+$412M-43bp on fee · 58× the assets · +$412M in over the monthHead-to-head
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