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Wednesday, October 28, 2026 · Today’s edition, 6:30 a.m. ETWed, Oct 28 · 6:30 a.m. editionSign inMy Desk 0EditionsSign in
PBEInvescoACTIVE

Invesco Dynamic Biotechnology & Genome ETF

$100.74+1.55% vs prior close
7310152-WK

Price through Oct 27, 2026 · Flows through Oct 26, 2026. Figures use the latest available records, not a live quote. Fund details retrieved Oct 27, 2026. Holdings snapshot retrieved Oct 27, 2026.

The fund generally will invest at least 90% of its total assets in the securities that comprise the underlying intellidex. The underlying intellidex was composed of common stocks of U.S. biotechnology and genome companies. These companies are engaged principally in the research, development, manufacture and marketing and distribution of various biotechnological products, services and processes, etc. It is non-diversified.

PBE price

Source: Market tape, daily closes; price return, distributions not reinvested
Table
DatePBE close
Sep 28, 2026$97.29
Sep 29, 2026$97.16
Sep 30, 2026$97.29
Oct 1, 2026$95.10
Oct 2, 2026$95.07
Oct 5, 2026$97.04
Oct 6, 2026$94.70
Oct 7, 2026$94.83
Oct 8, 2026$94.25
Oct 9, 2026$96.90
Oct 12, 2026$96.44
Oct 13, 2026$94.94
Oct 14, 2026$96.72
Oct 15, 2026$98.65
Oct 16, 2026$96.08
Oct 19, 2026$96.71
Oct 20, 2026$99.22
Oct 21, 2026$99.56
Oct 22, 2026$99.38
Oct 23, 2026$98.72
Oct 26, 2026$99.21
Oct 27, 2026$100.74

Daily net flows, 1M

Net outflow over the range: −$1M

  • Inflow / above zero
  • Outflow / below zero
Sep 28Sep 30Oct 2Oct 6Oct 8Oct 12Oct 14Oct 19Oct 21+$980K$0Oct 26Sep 28Sep 30Oct 2Oct 6Oct 8Oct 12Oct 14Oct 19Oct 21+$980K$0Oct 26Sep 28Oct 5Oct 12Oct 20+$980K$0Oct 26
Source: Daily creation and redemption records
Show as table
LabelValue ($)
Sep 28$0
Sep 29$0
Sep 30$0
Oct 1$0
Oct 2$950K
Oct 5−$960K
Oct 6−$960K
Oct 7$0
Oct 8$0
Oct 9$0
Oct 12−$970K
Oct 13$0
Oct 14$0
Oct 16$0
Oct 19$0
Oct 20$0
Oct 21$0
Oct 22$0
Oct 23$980K
Oct 26$0
The desk’s read

Money is leaving — −$960K in net outflows over the past month, about 0.2% of the fund's asset base, while the price has returned +22.6% so far this year. At 0.58% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$432Massets under management
0.58%expense ratio · $58 per $10,000 a year
−$960Knet flow, trailing month
13Kavg daily volume, 30 days
31holdings · US-domiciled
2005listed June 23, 2005 · beta 0.64
The book at a glance
ILMN+3.1%NTRA+1.5%BIIB+0.2%GILD+0.2%RPRX+0.8%AMGN+0.7%REGN+1.0%VRTX+0.7%MRNA+4.6%HALO+0.4%EXEL+0.4%QGEN-0.4%VCYT+4.3%UTHR-0.3%NVAX+6.6%TGTX+3.0%LEGN+5.7%VCEL+0.5%SRPT+5.1%RGEN-2.4%NBIX+0.1%PTGX+0.6%INCY+2.9%ANAB+1.8%PTCT+1.7%COLL-0.9%BMRN-0.7%BCRX+2.8%ARDX+0.0%ACAD+2.2%

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS

Holdings
#HoldingWeightPriceDay52-wk
1ILMNILLUMINA5.98%$279.47+3.1%
2NTRANATERA5.97%$410.82+1.5%
3BIIBBIOGEN5.67%$252.73+0.2%
4GILDGILEAD SCIENCES5.30%$159.08+0.2%
5RPRXROYALTY PHARMA5.18%$65.28+0.8%
6AMGNAMGEN4.99%$447.95+0.7%
7REGNREGENERON PHARMACEUTICALS4.81%$816.10+1.0%
8VRTXVERTEX PHARMACEUTICALS4.65%$521.03+0.7%
9MRNAMODERNA3.39%$207.97+4.6%
10HALOHALOZYME THERAPEUTICS3.17%$128.50+0.4%
11EXELEXELIXIS3.11%$65.35+0.4%
12QGENQIAGEN NV3.13%$50.17-0.4%
13VCYTVERACYTE2.96%$50.28+4.3%
14UTHRUNITED THERAPEUTICS3.10%$591.20-0.3%
15NVAXNOVAVAX2.70%$10.02+6.6%

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Sector weights

  • Healthcare100%
  • Health Technology91.43%
  • Health Services8.5%
  • Other0.1%
  • Mutual fund0.08%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
Healthcare100%
Health Technology91.43%
Health Services8.5%
Other0.1%
Mutual fund0.08%

Country weights

  • United States100%
  • Ireland3.05%
  • Netherlands2.73%
  • Canada2.43%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
United States100%
Ireland3.05%
Netherlands2.73%
Canada2.43%
Performance
1 week+1.2%
1 month+3.6%
3 months+12.1%
6 months+26.2%
YTD+22.6%
1 year+36.5%
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week+$980K
1 month−$960K
3 months+$111M
YTD+$113M
1 year+$113M

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows

  • Inflow / above zero
  • Outflow / below zero
−$17.5MAug−$3.5MSep$0Oct+$3.2MFeb−$5.4MMar+$30KApr−$1.6MMay+$1.6MJun+$4.6MJul+$161.2MAug−$50.1MSep−$960KOctAugSepOctFebMarAprMayJunJul+$161.2MAugSep−$960KOctAugOctMarMayJul+$161.2M−$960KOct
Source: Daily creation/redemption records, trailing twelve months
Show as table
LabelValue ($)
Aug−$17.5M
Sep−$3.5M
Oct$0
Feb$3.2M
Mar−$5.4M
Apr$30K
May−$1.6M
Jun$1.6M
Jul$4.6M
Aug$161.2M
Sep−$50.1M
Oct−$960K
The risk read
25%realized volatility, 30 days (annualized)
20%realized volatility, 1 year
-11.8%deepest fall from a peak, 1 year
at peaklatest close versus that peak

The top holding is 6.0% of the book; the top ten carry 49%. Spread across 32+ names, it behaves like roughly 26 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
—calls · latest snapshot
—puts · latest snapshot
—put/call ratio
5Kshares traded
Most-traded holdings, options premiumBullishBearish
MRNA MODERNA$52M$53M
AMGN AMGEN$64M$2M
NTRA NATERA$2M$2M
GILD GILEAD SCIENCES$2M$738,877
REGN REGENERON PHARMACEUTICALS$752,963$1M

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against PBE

Due diligence cuts both ways. These funds sit on the same shelf and beat PBE on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW SPDR Portfolio Developed World ex-US ETF0.03%$40.7B+$609M-55bp on fee · 94× the assets · +$609M in over the monthHead-to-head
BBUS JPMorgan BetaBuilders U.S. Equity ETF0.02%$9.6B+$187M-56bp on fee · 22× the assets · +$187M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.4B+$199M-55bp on fee · 42× the assets · +$199M in over the monthHead-to-head
SPYG State Street SPDR Portfolio S&P 500 Growth ETF0.04%$57.9B+$717M-54bp on fee · 134× the assets · +$717M in over the monthHead-to-head
SPTM State Street SPDR Portfolio S&P 1500 Composite Stock Market ETF0.03%$14.2B+$235M-55bp on fee · 33× the assets · +$235M in over the monthHead-to-head
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