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Wednesday, October 28, 2026 · Today’s edition, 6:30 a.m. ETWed, Oct 28 · 6:30 a.m. editionSign inMy Desk 0EditionsSign in
XPHSPDRINDEX

SPDR S&P Pharmaceuticals ETF

$63.96+1.69% vs prior close
487452-WK

Price through Oct 27, 2026 · Flows through Oct 26, 2026. Figures use the latest available records, not a live quote. Fund details retrieved Oct 27, 2026. Holdings snapshot retrieved Oct 27, 2026.

In seeking to track the performance of the S&P Pharmaceuticals Select Industry Index (the "index"), the fund employs a sampling strategy. It generally invests substantially all, but at least 80%, of its total assets in the securities comprising the index. The index represents the pharmaceuticals segment of the S&P Total Market Index ("S&P TMI").

XPH price

Source: Market tape, daily closes; price return, distributions not reinvested
Table
DateXPH close
Sep 28, 2026$66.89
Sep 29, 2026$66.09
Sep 30, 2026$65.00
Oct 1, 2026$63.78
Oct 2, 2026$63.64
Oct 5, 2026$63.66
Oct 6, 2026$62.91
Oct 7, 2026$62.91
Oct 8, 2026$63.63
Oct 9, 2026$64.65
Oct 12, 2026$64.01
Oct 13, 2026$62.10
Oct 14, 2026$62.07
Oct 15, 2026$63.02
Oct 16, 2026$61.84
Oct 19, 2026$62.24
Oct 20, 2026$64.15
Oct 21, 2026$63.96
Oct 22, 2026$64.28
Oct 23, 2026$62.70
Oct 26, 2026$62.90
Oct 27, 2026$63.96

Daily net flows, 1M

Net outflow over the range: −$80M

  • Inflow / above zero
  • Outflow / below zero
Sep 28Sep 30−$22.4MOct 2Oct 6Oct 8Oct 12Oct 14Oct 16Oct 20Oct 22$0Oct 26Sep 28Sep 30−$22.4MOct 2Oct 6Oct 8Oct 12Oct 14Oct 16Oct 20Oct 22$0Oct 26Sep 28−$22.4MOct 5Oct 12Oct 19$0Oct 26
Source: Daily creation and redemption records
Show as table
LabelValue ($)
Sep 28−$6.6M
Sep 29$0
Sep 30−$6.6M
Oct 1−$3.2M
Oct 2−$22.4M
Oct 5$0
Oct 6−$18.9M
Oct 7−$9.4M
Oct 8$3.1M
Oct 9$0
Oct 12−$3.2M
Oct 13$0
Oct 14−$3.1M
Oct 15$0
Oct 16$0
Oct 19−$6.2M
Oct 20$0
Oct 21$0
Oct 22−$3.2M
Oct 23$0
Oct 26$0
The desk’s read

Money is leaving — −$80M in net outflows over the past month, about 18.1% of the fund's asset base, while the price has returned +14.2% so far this year. At 0.35% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$440Massets under management
0.35%expense ratio · $35 per $10,000 a year
−$80Mnet flow, trailing month
198Kavg daily volume, 30 days
41holdings · US-domiciled
2006listed June 19, 2006 · beta 0.76
The book at a glance
AMLX+4.5%OMER+7.4%MBX+5.3%DFTX+3.9%PCRX+0.1%MANE+2.4%PRGO+1.3%AMRX+2.0%MAZE+2.0%LGND+1.1%ETON+2.0%XERS+2.4%EWTX+0.9%RPRX+0.8%MRK+0.9%VTRS+2.4%ELVN+5.3%PFE+0.0%TARS+1.0%LLY+0.2%JNJ+0.9%CORT+0.5%BMY-0.1%HRMY+3.0%AMPH+0.4%PAHC-1.7%OGN+0.1%TRVI+6.7%NUVB+0.9%ELAN-1.4%PBH-1.6%ZTS-3.4%INDV+0.5%INVA-0.5%SUPN+0.5%JAZZ+0.5%ANIP-2.0%SEPN+6.7%HROW+0.4%OCUL+3.9%

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS

Holdings
#HoldingWeightPriceDay52-wk
1AMLXAMYLYX PHARMACEUTICALS2.04%$28.30+4.5%
2OMEROMEROS1.42%$17.49+7.4%
3MBXMBX Biosciences2.72%$52.97+5.3%
4DFTXDefinium Therapeutics3.09%$37.08+3.9%
5PCRXPACIRA BIOSCIENCES1.65%$36.40+0.1%
6MANEVERADERMICS INC2.02%$140.72+2.4%
7PRGOPERRIGO CO1.42%$16.02+1.3%
8AMRXAMNEAL PHARMACEUTICALS1.72%$21.44+2.0%
9MAZEMaze Therapeutics1.85%$31.69+2.0%
10LGNDLIGAND PHARMACEUTICALS1.94%$311.73+1.1%
11ETONETON PHARMACEUTICALS1.30%$51.16+2.0%
12XERSXERIS BIOPHARMA HOLDINGS1.39%$10.45+2.4%
13EWTXEDGEWISE THERAPEUTICS1.88%$39.53+0.9%
14RPRXROYALTY PHARMA1.57%$65.28+0.8%
15MRKMERCK & CO1.65%$141.82+0.9%

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Sector weights

  • Healthcare100%
  • Health Technology99.68%
  • Other0.33%
  • Mutual fund0.32%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
Healthcare100%
Health Technology99.68%
Other0.33%
Mutual fund0.32%

Country weights

  • United States99.6%
  • Ireland9.31%
  • Singapore0.4%
  • Cayman Islands0.39%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
United States99.6%
Ireland9.31%
Singapore0.4%
Cayman Islands0.39%
Performance
1 week0.0%
1 month-3.2%
3 months-6.7%
6 months+11.4%
YTD+14.2%
1 year+30.2%
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week−$3M
1 month−$80M
3 months+$11M
YTD+$186M
1 year+$206M

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows

  • Inflow / above zero
  • Outflow / below zero
+$5.3MNov+$14.8MDec+$61.6MJan+$28.4MFeb$0Mar+$25.3MApr−$5.5MMay+$27.4MJun+$51.5MJul+$78.7MAug−$15.3MSep−$66.5MOctNovDecJanFebMarAprMayJunJul+$78.7MAugSep−$66.5MOctNovJanMarMayJul+$78.7M−$66.5MOct
Source: Daily creation/redemption records, trailing twelve months
Show as table
LabelValue ($)
Nov$5.3M
Dec$14.8M
Jan$61.6M
Feb$28.4M
Mar$0
Apr$25.3M
May−$5.5M
Jun$27.4M
Jul$51.5M
Aug$78.7M
Sep−$15.3M
Oct−$66.5M
The risk read
24%realized volatility, 30 days (annualized)
24%realized volatility, 1 year
-16.5%deepest fall from a peak, 1 year
-13.6%latest close versus that peak

The top holding is 3.1% of the book; the top ten carry 22%. Spread across 66+ names, it behaves like roughly 60 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
1calls · latest snapshot
—puts · latest snapshot
—put/call ratio
50Kshares traded
Most-traded holdings, options premiumBullishBearish
LLY ELI LILLY$24M$26M
MRK MERCK & CO$3M$4M
JNJ JOHNSON & JOHNSON$4M$3M
LQDA LIQUIDIA$2M$3M
PFE PFIZER$2M$2M

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against XPH

Due diligence cuts both ways. These funds sit on the same shelf and beat XPH on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW SPDR Portfolio Developed World ex-US ETF0.03%$40.7B+$609M-32bp on fee · 92× the assets · +$609M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.4B+$199M-32bp on fee · 42× the assets · +$199M in over the monthHead-to-head
IDEV iShares Core MSCI International Developed Markets ETF0.04%$32.4B+$497M-31bp on fee · 74× the assets · +$497M in over the monthHead-to-head
IGSB iShares 1-5 Year Investment Grade Corporate Bond ETF0.04%$23.7B+$47M-31bp on fee · 54× the assets · +$47M in over the monthHead-to-head
IGIB iShares 5-10 Year Investment Grade Corporate Bond ETF0.04%$18.6B+$412M-31bp on fee · 42× the assets · +$412M in over the monthHead-to-head
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